Mechanism of JmjC-containing protein Hairless in the regulation of vitamin D receptor function
نویسندگان
چکیده
منابع مشابه
Mechanism of JmjC-containing protein Hairless in the regulation of vitamin D receptor function.
The JmjC-domain-containing protein Hairless (HR) and the vitamin D receptor (VDR) play a critical role in the maintenance of hair growth. Mutations in HR or VDR cause alopecia in humans and mice. Here we show that HR interacts with VDR and induces VDR relocalization in the nuclei. HR associates and colocalizes with nuclear receptor co-repressor (N-CoR) which is localized to subnuclear structure...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2011
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2011.09.015